Other Bags to Check Out:
The Monolith Weekender from Heimplanet is one of my favorites because it is very durable and simple. Carries all your shit, and comfortably!
A medium-large sized travel bag with sturdy, rigid outer material, a couple external pockets and a removable internal divider that makes for actually a pretty interesting way of accessing things in transit.
The Topo Travel bag has a playful style, which I like a lot, but it is very serious about being a great travel bag. This is a classic.
The Outbreaker backpack from Tortuga is a solid 1-bag travel pick. I personally prefer the less bulky (and more spacious) experience of traveling with the Tortuga Setout, so be sure to check out that bag too. This Outbreaker, however, has quite a bit more padding and protection around the entire bag, so if you know you'll have delicate stuff inside you may prefer this one.
The Viken from YNOT is as simple and sturdy a duffel as a modern urbanite could ask for. And it expands. Just lovely.