The Simple Office bag from Qwstion is an excellent convertible briefcase/backpack with organization and aesthetics that fit many modern city folks.
Other Bags to Check Out:
The Setout Laptop Backpack from Tortuga is an excellent bag for minimal travel AND daily carry.
An utterly functional daypack in a tight little package with some modern metro styling.
This is what I call the "badass bargain option." Everything you need in a daily carry, organized innovatively so it stays fun to use, and it's super affordable.
The Staad Backpack from Waterfield almost looks like a piece of art. It's beautifully designed (and functional as a mthrfkr!).